// Oxymetholone · DHT Derivative · 320:45 Ratio · Oral + Injectable · Highest Acute Anabolic

AnadrolOxymetholone — Highest Acute Anabolic Oral AAS Reference by QSC Peptides

Anadrol (Oxymetholone) is a DHT-derived oral AAS and among the most potent anabolic compounds by acute response. 320:45 anabolic:androgenic ratio. Available in oral tablet and injectable oil forms from QSC Peptides. ≥99% purity, free USA USPS/FedEx.

Compound Profile

Parent StructureDHT (2-hydroxymethylene)
Anabolic:Androgenic320:45
AromatizationDoes not aromatize*
Estrogenic ActivityYes (ER agonist, not E2)
C17α AlkylationYes (oral)
Half-Life~8–9 hours
FormsOral + Injectable
QSC Purity≥99%
QSC Peptides ≥99% Purity Verified COA Every Order Free USA USPS/FedEx US Domestic Stock 8 Warehouse Regions
// Mechanism of Action

How Anadrol Works

Anadrol (Oxymetholone) is a DHT derivative with a 2-hydroxymethylene group on the A-ring. Despite being derived from DHT (which does not aromatize), oxymetholone exerts significant estrogenic activity through a direct agonist action at the estrogen receptor — not through aromatization — making it a pharmacologically unusual AAS compound for research.

Oxymetholone binds AR with moderate affinity, but in vivo demonstrates among the highest acute anabolic responses of any oral AAS (320:45 ratio). The discrepancy between in vitro AR binding and in vivo anabolic response suggests additional mechanisms — possibly including IGF-1 axis stimulation, progestogenic activity, or ER-mediated anabolic contributions.

Estrogenic Activity Without Aromatization

Despite not aromatizing via CYP19A1, oxymetholone has been documented to act as a direct estrogen receptor agonist. This makes Anadrol uniquely valuable in research designed to separate AR-mediated from ER-mediated anabolic effects — comparing oxymetholone to non-estrogenic AAS (Anavar, Winstrol) allows dissection of which anabolic outcomes require ER co-activation.

// Research Applications

Research Applications

  • Oral AAS maximum potency: Oxymetholone as the high-potency reference for acute oral anabolic response
  • ER agonism without aromatization: Unique model for estrogen receptor activation via direct binding — without CYP19A1
  • Mechanistic anabolic research: Dissecting AR vs ER contributions to muscle protein synthesis using oxymetholone vs non-estrogenic AAS
  • Anemia research: Oxymetholone is FDA-approved for aplastic anemia — erythropoiesis, EPO stimulation mechanisms
  • Hepatocellular biology: C17α-AA hepatotoxicity model — oxymetholone as one of the more hepatotoxic oral AAS
  • IGF-1 axis: Potential indirect IGF-1 stimulation contributing to acute anabolic response
// QSC Peptides Products

Buy Anadrol from QSC Peptides

Research-grade · ≥99% purity · COA · Free USA USPS/FedEx · US domestic warehouse

Oral
Anadrol 50mg Tablets | 100-Count
Oxymetholone · Highest Anabolic Rating

QSC Peptides · 320:45 ratio

≥99% Pure · COA
Injectable
Anadrol 50mg/mL Injectable | 10-Vial
Oxymetholone · Oil-based

QSC Peptides

≥99% Pure · COA
// FAQ

Frequently Asked Questions

Anadrol is oxymetholone — a DHT-derived oral AAS with 320:45 anabolic:androgenic ratio. Notable for the highest acute anabolic response of any oral AAS, and for direct ER agonist activity without aromatization — a pharmacologically unique profile. QSC Peptides offers 50mg tablets and 50mg/mL injectable.
Oxymetholone acts as a direct estrogen receptor (ER) agonist — binding ER without requiring conversion to estradiol via CYP19A1. This is one of few AAS with ER agonist activity independent of aromatization, making it a unique research tool for separating AR from ER anabolic contributions.
Yes. Free USPS/FedEx from US domestic warehouse on all orders.
// Related Compounds

Related AAS Research Compounds

Dianabol
Most Popular Oral
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Anavar
High Selectivity Oral
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Winstrol
DHT Oral
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Testosterone
Reference Compound
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